Episodes

Monday Jan 31, 2022
Episode 125: Earthquakes
Monday Jan 31, 2022
Monday Jan 31, 2022
A discussion of earthquakes, covering the elastic rebound theory of earthquake generation, the phenomena of deep and intraplate earthquakes, types of seismic waves, methods of earthquake detection, different ways in which earthquakes cause damage, and attempts at earthquake prediction. Recommended pre-listening is Episode 111: Plate Tectonics.
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Thursday Dec 30, 2021
Episode 124: Volcanoes
Thursday Dec 30, 2021
Thursday Dec 30, 2021
A discussion of the awesome power of volcanoes, including an overview of the different types of volcanoes, types of lava and pyroclastics, mechanisms of volcanic eruptions, a curvey of volcanic landforms, and a review of some major historical eruptions and their effects on Earth's climate. Recommended pre-listening is Episode 111: Plate Tectonics.
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Tuesday Nov 30, 2021
Episode 123: Respiratory and Circulatory Systems Part 2
Tuesday Nov 30, 2021
Tuesday Nov 30, 2021
Concluding the two-part series on the circulatory and respiratory systems, I discuss the biochemical mechanisms by which red blood cells and hemoglobin molecules deliver oxygen to the tissues and carbon dioxide to the lungs, and the mechanisms which regulate these processes. I then consider the respiratory system, giving an overview of the structure and function of the lungs, the process of breathing, control of breathing, and adaptations to high altitudes. Recommended pre-listening is Episode 122: Respiratory and Circulatory Systems Part 2.
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Sunday Oct 31, 2021
Episode 122: Respiratory and Circulatory Systems Part 1
Sunday Oct 31, 2021
Sunday Oct 31, 2021
The first in a two-part episode covering the circulatory and respiratory systems, including a discussion of the anatomy of the heart, the process of contraction, and the generation and propagation of electrical activity. I also discuss how the heart functions as a pump, the various types of blood vessels, and control of the heart rate by the brain. Recommended pre-listening is Episode 25: Tissues, Organs and Systems, and Episode 26: Human Organ Systems.
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Sunday Sep 12, 2021
Episode 121: The Biology of Pain
Sunday Sep 12, 2021
Sunday Sep 12, 2021
An overview of the underlying mechanisms of pain, including the role of nociception, transduction of nociceptor signals by spinal pathways, the modulatory effects of opioids, and processing of these inputs in the brain. I also discuss phenomena such as referred pain, psychogenic pain, and congenital insensitivity to pain.
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Saturday Jul 31, 2021
Episode 120: Computational Chemistry Part 2
Saturday Jul 31, 2021
Saturday Jul 31, 2021
Building on the previous discussion of Hartree-Fock Theory, I discuss the inclusion of basis functions to produce the Roothaan equations, and the method of solving these using self-consistent field methods. I then provide an introduction into techniques to incorporate electron correlation by adding Slater determinants, focusing on the Configuration Interaction method. I then provide a brief overview of semi-empirical methods, Density Functional Theory, and molecular mechanics. Recommended pre-listening is Episode 119: Computational Chemistry Part 1.
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Wednesday Jun 30, 2021
Episode 119: Computational Chemistry Part 1
Wednesday Jun 30, 2021
Wednesday Jun 30, 2021
An overview of techniques of determining molecular structure, including an introduction to valance bond theory covering bond formation and orbital hybridisation, and a discussion of the basics of molecular orbital theory, covering the basics of the Hartree-Fock method for solving the Schrödinger equation and finding molecular orbitals. In the process I also discuss the Pauli exclusion principle, the effect of electron spin, and the indistinguishability of electrons.
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Monday May 31, 2021
Episode 118: Cell Signalling
Monday May 31, 2021
Monday May 31, 2021
A discussion of cell communication and signalling, including an overview of the purpose of cell signalling, the main types of signals, and applications such as hormones, neurotransmitters, and cytokines. The difference between G protein-coupled receptors, enzyme-linked receptors, and intracellular receptors is also considered, concluding with a summary of the process of signal transduction and the role of second messengers. Recommended pre-listening is Episode 116: The Cell Membrane.
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Saturday May 01, 2021
Episode 117: Intracellular Protein Sorting
Saturday May 01, 2021
Saturday May 01, 2021
A discussion of the transportation and sorting of proteins within the eukaryotic cell, including an overview of the endomembrane system, the mechanisms of nuclear transport, transmembrane transport, and vesicular transport. I also consider the structure and functions of the endoplasmic reticulum, the Golgi apparatus, and lysosomes, and how they are joined together in a complex network of protein transportation and vesicular traffic. Recommended pre-listening is Episode 116: The Cell Membrane.
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Wednesday Mar 31, 2021
Episode 116: The Cell Membrane
Wednesday Mar 31, 2021
Wednesday Mar 31, 2021
An introduction to the cell membrane, including a discussion of the structure of the bilipid membrane, an overview of the structure and function of membrane proteins, a review of the fluid mosaic model, and a discussion of mechanisms of membrane transport, including both passive and active transport. Recommended pre-listening is Episode 10: The Cell, and Episode 18: Biochemistry Basics.
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